Liewei Wang Selected Research

Metformin (Glucophage)

1/2021	ZNF423 modulates the AMP-activated protein kinase pathway and metformin response in a single nucleotide polymorphisms, estrogen and selective estrogen receptor modulator dependent fashion.
1/2019	The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer.
1/2018	Machine Learning Helps Identify New Drug Mechanisms in Triple-Negative Breast Cancer.
4/2017	Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer.
11/2016	Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines.
1/2015	Leveraging an Electronic Health Record-Linked Biorepository to Generate a Metformin Pharmacogenomics Hypothesis.

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Liewei Wang Research Topics

Disease

69	Neoplasms (Cancer) 06/2022 - 09/2008
66	Breast Neoplasms (Breast Cancer) 06/2022 - 12/2005
15	Major Depressive Disorder (Major Depressive Disorders) 11/2022 - 03/2013
14	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2015
12	Triple Negative Breast Neoplasms 06/2022 - 11/2016
9	Drug-Related Side Effects and Adverse Reactions 02/2021 - 09/2003
6	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2015
6	Pancreatic Neoplasms (Pancreatic Cancer) 12/2016 - 06/2010
5	Lung Neoplasms (Lung Cancer) 01/2021 - 06/2011
4	Stroke (Strokes) 01/2020 - 01/2011
3	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2021 - 01/2019
3	Hematologic Neoplasms (Hematological Malignancy) 01/2021 - 01/2018
3	Myocardial Infarction 01/2020 - 01/2011
3	T-Cell Leukemia (Leukemia, T Cell) 01/2018 - 03/2012
3	Leukemia 09/2017 - 01/2012
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2012 - 06/2011
3	Carcinogenesis 08/2011 - 03/2006
2	Rheumatoid Arthritis 01/2022 - 01/2022
2	Multiple Myeloma 01/2021 - 06/2008
2	Thrombosis (Thrombus) 01/2021 - 01/2020
2	Hemorrhage 01/2020 - 01/2020
2	Inflammation (Inflammations) 01/2019 - 01/2017
2	Circulating Neoplastic Cells 01/2018 - 08/2017
2	Pathologic Complete Response 01/2018 - 01/2017
2	Musculoskeletal Pain 03/2016 - 03/2012
2	Adenocarcinoma 02/2016 - 01/2013
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 03/2014 - 12/2010
1	Fatigue 11/2022

Drug/Important Bio-Agent (IBA)

29	Pharmaceutical PreparationsIBA 06/2022 - 09/2004
17	Aromatase InhibitorsIBA 10/2021 - 12/2005
17	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 06/2008
15	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2012
14	Estrogens (Estrogen)FDA Link 01/2022 - 12/2005
13	Estrogen ReceptorsIBA 01/2021 - 04/2013
11	Gemcitabine FDA Link 12/2016 - 09/2008
10	Small Interfering RNA (siRNA)IBA 12/2016 - 11/2009
9	Anastrozole (Arimidex)FDA LinkGeneric 01/2022 - 01/2010
8	Proteins (Proteins, Gene)FDA Link 06/2022 - 08/2011
7	Biological ProductsIBA 06/2022 - 06/2011
7	Androgen Receptors (Androgen Receptor)IBA 06/2022 - 01/2017
7	RNA (Ribonucleic Acid)IBA 03/2019 - 12/2014
6	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2021 - 03/2013
6	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 01/2015
5	Phenobarbital (Luminal)FDA Link 06/2022 - 01/2017
5	exemestane (Aromasin)FDA Link 01/2022 - 12/2016
5	Aromatase (CYP19)IBA 01/2020 - 12/2005
5	Estradiol (Delestrogen)FDA LinkGeneric 01/2020 - 01/2010
5	Selective Estrogen Receptor Modulators (SERM)IBA 08/2017 - 07/2013
5	CytidineIBA 02/2014 - 09/2008
4	abirateroneIBA 01/2022 - 08/2017
4	AnthracyclinesIBA 01/2022 - 12/2017
4	Trastuzumab (Herceptin)FDA Link 01/2022 - 12/2017
4	Antidepressive Agents (Antidepressants)IBA 10/2021 - 08/2018
4	Phosphotransferases (Kinase)IBA 01/2021 - 12/2018
4	AndrogensIBA 01/2021 - 01/2015
4	taxaneIBA 01/2021 - 09/2012
4	Tamoxifen FDA LinkGeneric 01/2021 - 07/2013
4	Bevacizumab (Avastin)FDA Link 01/2018 - 01/2012
4	P-2 (P 2)IBA 10/2017 - 07/2013
3	Long Noncoding RNAIBA 12/2021 - 12/2016
3	Docetaxel (Taxotere)FDA Link 01/2021 - 09/2012
3	enzalutamideIBA 01/2021 - 01/2015
3	Abiraterone AcetateIBA 12/2020 - 08/2017
3	Estrone FDA Link 01/2020 - 01/2010
3	EnzymesIBA 01/2019 - 12/2005
3	Cisplatin (Platino)FDA LinkGeneric 12/2018 - 09/2011
3	olaparibIBA 12/2018 - 01/2017
3	Hypoglycemic Agents (Hypoglycemics)IBA 01/2018 - 01/2015
3	Messenger RNA (mRNA)IBA 11/2017 - 12/2014
3	2-mercaptopurineIBA 03/2014 - 09/2003
2	Letrozole (Femara)FDA LinkGeneric 01/2022 - 01/2020
2	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 01/2022
2	GlucocorticoidsIBA 12/2021 - 01/2018
2	Clopidogrel (Plavix)FDA Link 01/2021 - 01/2020
2	Cytochrome P-450 CYP2C19IBA 01/2021 - 01/2020
2	Aurora Kinase AIBA 01/2021 - 01/2018
2	Tyrosine (L-Tyrosine)FDA Link 01/2021 - 12/2018
2	Prednisone (Sone)FDA LinkGeneric 12/2020 - 01/2018
2	LigandsIBA 01/2020 - 08/2017
2	Therapeutic UsesIBA 11/2019 - 09/2008
2	MethyltransferasesIBA 11/2019 - 01/2018
2	Nucleic AcidsIBA 03/2019 - 09/2008
2	Escitalopram FDA Link 01/2019 - 01/2019
2	Citalopram FDA LinkGeneric 01/2019 - 01/2019
2	Protein Kinases (Protein Kinase)IBA 01/2018 - 01/2015
2	Estrogen Receptor alphaIBA 01/2018 - 01/2017
2	HomocysteineIBA 01/2018 - 03/2014
2	Paclitaxel (Taxol)FDA LinkGeneric 11/2017 - 09/2012
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 11/2015 - 10/2015
2	Raloxifene Hydrochloride (Evista)FDA Link 01/2015 - 07/2013
1	Fluoxetine (Prozac)FDA LinkGeneric 11/2022
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 11/2022
1	AMP-Activated Protein KinasesIBA 06/2022

Therapy/Procedure

48	Therapeutics 06/2022 - 01/2010
33	Drug Therapy (Chemotherapy) 01/2022 - 09/2004
12	Neoadjuvant Therapy 06/2022 - 01/2010
9	Castration 01/2022 - 08/2017
3	Radiotherapy 01/2021 - 11/2010
3	Precision Medicine 12/2018 - 01/2015
2	Stents 01/2021 - 01/2020